Secreted Enzyme-Responsive System for Controlled Antifungal Agent Release

Enzyme and voltage stimuli-responsive controlled release system based on β-cyclodextrin-capped mesoporous silica nanoparticles.

Enzyme and voltage stimuli are more biologically compatible in the field of stimuli-responsive systems and release systems based on β-cyclodextrin (CD) and ferrocene (Fc) have attracted much attention. Herein, mesoporous silica nanoparticles (MSNs) have been functionalized with the ferrocenyl moiety (Fc) which interacts with β-cyclodextrin (β-CD) to form an inclusion complex on the opening of t...

A glucose-responsive controlled release of insulin system based on enzyme multilayers-coated mesoporous silica particles.

A novel glucose-responsive controlled release of insulin system is constructed through coating enzyme multilayers on mesoporous silica particles (MSPs). The MSPs serve as the drug reservoir, and the enzyme multilayers cross-linked with glutaraldehyde act as a valve to control the release of insulin in response to the external glucose level.

A secreted enzyme reporter system for MRI.

An important goal in modern biology is to understand how molecular processes commonly studied at the cellular level give rise to physiological functions in complex tissues and organisms. Noninvasive imaging of gene expression patterns in whole animals could provide information critical to this end but current methods lack sensitivity and spatiotemporal precision. Enzymatic reporter systems dete...

Characterization of enzyme sensitive responsive hydrogel/lipid system for triggered release

A pH-driven DNA nanoswitch for responsive controlled release.

An intelligent pH-responsive carrier and release system based on DNA nanoswitch-controlled organization of gold nanoparticles (AuNPs) attached to mesoporous silica (MS) has been designed and demonstrated.